What is Acanthamoeba Keratitis
Acanthamoeba keratitis (acant: hamoeba keratitis) is an infection caused by Acanthamoeba keratitis, a serious threat to vision, usually presents with chronic, progressive corneal ulcers, the course for a few months.
Symptoms of Acanthamoeba Keratitis
The symptoms of Acanthamoeba keratitis: similar to herpes simplex keratitis, bacterial keratitis, fungal keratitis, often unilateral disease, bilateral rare. The incidence initial foreign body sensation, photophobia, lacrimation, and vision loss. The initial presentation of epithelial opacities false dendritic or local punctate fluorescein staining. Gradually expanded into a matrix infiltration and infiltration along the radial distribution of corneal nerves, called radial keratotomy neuritis. In this case there is a severe eye pain. Then the matrix formation of inflammatory infiltration ring circumferential white satellite lesions, the central matrix resembling discoid keratitis, often hypopyon. Can Descemet folds, KP and repeated epithelial exfoliation.
What Causes Acanthamoeba Keratitis
The cause of Acanthamoeba keratitis: Acanthamoeba is mainly present in the soil, fresh water, sea water, swimming pool, air, grain and livestock. It can resist freezing, drying and conventional concentration of chlorine in the city water supply, swimming pool, tub kill. The disease is often a result of the cornea contact with Acanthamoeba contaminated water sources, especially through contaminated contact lens or lens cleaning liquid medicine infected with the disease.
Tests and Diagnosis for Acanthamoeba Keratitis
Diagnosis of Acanthamoeba keratitis: corneal lesions derived after smear, can be found in Acanthamoeba or culture of the Acanthamoeba. When necessary, can be used for corneal biopsy. Preservation solution, contact lens cleaning fluid pathogens check the diagnosis. Confocal laser microscope can be found in Acanthamoeba trophozoites and cysts.
Treatments of Acanthamoeba Keratitis
Treatment of Acanthamoeba keratitis choice of two microphones or associated microphone drugs (such as 0.15% isethionic double bromine imipramine), imidazole of 101mg/ml miconazole) medicines (such as eye drops or eye ointment dosage first frequency and then decreases over the course of 4 months. Plus the imidazoles drug orally. Glucocorticoid drugs can make the disease progression, and generally do not advocate the use of. If the lesion is localized, drug treatment failure, or drug treatment residual seriously affect the vision of the corneal opacity (infection has full control, the inflammation has subsided), which may be imposed by penetrating keratoplasty. When the cornea upcoming perforation penetrating keratoplasty, is also feasible. Acanthamoeba keratitis should continue after the drug treatment, and reduce recurrence. Infection range is difficult to accurately determine the preoperative, intraoperative difficult lesion excision.